Sodium normal range (and what it means for nurses)

Normal serum sodium is 136 to 145 mEq/L in the UW Medicine lab table the MagstoneRN app uses, and section 15.4 of Open RN's Nursing Fundamentals agrees. Below 136 is hyponatremia; above 145 is hypernatremia. Both shift water into or out of brain cells; watch for confusion. Ranges differ between labs, so use the range on the patient's report.[1][2][3]

Start monthly 5-day trial

Payment method required. First-time subscribers only. After the trial, the plan costs $19.99/month until you cancel. You aren't charged if you cancel before the trial ends. Cancel anytime online.

Quick facts

Serum sodium reference range and serum osmolality
TestRangeUnitApplies to
Sodium (serum or plasma)[1][2]136-145mEq/LAll ages
Hyponatremia (low)[1][2]Below 136mEq/LAll ages
Hypernatremia (high)[1][2]Above 145mEq/LAll ages
Serum osmolality[2]275-295mmol/kgPopulation not stated

Both high and low sodium show up as neurological changes

  • Low sodium moves water into brain cells and they swell, so expect headache, confusion and seizures. Without treatment, very low sodium can lead to coma.[2][4]
  • High sodium pulls water out of cells, and the effect is most noticeable in the brain: confusion, irritability, lethargy and even seizures, along with intense thirst and sticky mucous membranes.[2]

Think about water first: lost water raises sodium, extra water dilutes it

  • High sodium usually comes from water loss, such as too little fluid intake, vomiting or diarrhea. As fluid is lost and sodium climbs, serum osmolality rises too.[2]
  • Low sodium can follow too much water or too much hypotonic IV fluid. Heart failure, kidney disease, cirrhosis and some medicines, such as many nonprescription pain relievers and some antidepressants, can also lower it.[2][4]
  • Treatment of low sodium depends on the cause and often means limiting water or stopping hypotonic IV fluid. If hyponatremia is severe, prescribed hypertonic saline raises sodium gradually.[2]

Diuretics can drop sodium along with potassium

  • For patients on diuretics, watch for fluid volume deficit and for both low sodium and low potassium.[2]

Sodium and the rest of the panel are in the Basic metabolic panel flashcard deck. Find the deck in the free app preview.

Open the free app preview

How it shows up on nursing exams

  • Work every sodium question through neuro status and fluid status. A falling sodium with new confusion is a change to report now, not one to recheck tomorrow.[2][4]
  • Extra free water is the wrong move for a low sodium, because excess water intake is one of its causes.[2]

Practice question

A 72-year-old patient admitted with pneumonia has a serum sodium of 127 mEq/L this morning, down from 137 mEq/L yesterday. The laboratory reference range is 136 to 145 mEq/L. The patient is newly confused and reports a headache. Blood pressure is 126/78 mm Hg, heart rate 86/min, respiratory rate 18/min, and SpO2 95% on room air. Furosemide and acetaminophen are scheduled now. Which action should the nurse take first?

  1. A. Offer the patient extra water to drink
  2. B. Report the sodium drop and new confusion
  3. C. Give the furosemide dose scheduled now
  4. D. Recheck the sodium level with tomorrow's labs
Show the answer and why

Correct answer: B. Report the sodium drop and new confusion

  • A. Incorrect. Excess water intake is a cause of hyponatremia, so more water could lower the sodium further.
  • B. Correct. The sodium is below 136 and falling, and headache and confusion are neurological signs of hyponatremia, which can also cause seizures and coma. The provider needs this change now.
  • C. Incorrect. Diuretics are a cause of hyponatremia, so giving the dose before the new low sodium and confusion are reported could make the problem worse.
  • D. Incorrect. Waiting a day delays care for a sodium that is falling with new neurological signs. Very low sodium can become life-threatening without treatment.

Sources for this question: [1][2][4]

Memory hook: Sodium problems are water problems, and the warning signs are neurological.

Questions about sodium

What is a normal sodium level?

It is 136 to 145 mEq/L in UW Medicine's lab table, which the MagstoneRN app uses, and section 15.4 of Open RN's Nursing Fundamentals gives the same range. Ranges differ between labs, so use the range on the patient's report.[1][2][3]

What are the signs of low sodium?

Headache, confusion and seizures, because water moves into brain cells and they swell. Without treatment, very low sodium can lead to coma.[2][4]

Can diuretics cause low sodium?

Yes. Patients on diuretics are watched for fluid volume deficit and for both low sodium and low potassium.[2]

Study this topic in MagstoneRN

The Renal care and fluid balance deck covers the sodium disturbances that cause new confusion, and the Basic metabolic panel deck covers the lab itself.

Browse flashcards
Start monthly 5-day trial

Payment method required. First-time subscribers only. After the trial, the plan costs $19.99/month until you cancel. You aren't charged if you cancel before the trial ends. Cancel anytime online.

MagstoneRN plans and trial terms

Sources for this page

  1. Sodium, default method (reference interval effective September 14, 2026) (opens in a new tab). UW Medicine Laboratory Test Guide. License: Not openly licensed; reference values cited as facts, no text reused. Accessed October 18, 2026.
  2. Nursing Fundamentals, 2nd edition, Chapter 15: Fluids and Electrolytes (opens in a new tab). Open RN, Chippewa Valley Technical College (2024). License: CC BY 4.0. Accessed October 18, 2026.
  3. How to Understand Your Lab Results (updated September 4, 2025) (opens in a new tab). MedlinePlus, National Library of Medicine. License: Public domain (U.S. government work). Accessed October 18, 2026.
  4. Sodium Blood Test (updated December 2, 2024) (opens in a new tab). MedlinePlus, National Library of Medicine. License: Public domain (U.S. government work). Accessed October 18, 2026.

A number in brackets links to the source for the fact it follows.

Report a wrong or outdated fact through support and MagstoneRN will correct the page.

Sources: 4 entries, last accessed October 18, 2026.